By Tzvi Tzfira,Vitaly Citovsky

Agrobacterium is a plant pathogen which factors the “crown-gall” sickness, a neoplastic development that effects from the move of a well-defined DNA phase (“transferred DNA”, or “T-DNA”) from the bacterial Ti (tumor-inducing) plasmid to the host mobilephone, its integration into the host genome, and the expression of oncogenes contained at the T-DNA. The molecular equipment, wanted for T-DNA iteration and delivery into the host phone and encoded by way of a chain of chromosomal (chv) and Ti-plasmid virulence (vir) genes, has been the topic of diverse stories during the last numerous a long time. at the present time, Agrobacterium is the software of selection for plant genetic engineering with an ever increasing host variety that comes with many commercially vital vegetation, plant life, and tree species. in addition, its fresh program for the genetic transformation of non-plant species, from yeast to cultivated mushrooms or even to human cells, can provide this bacterium a distinct position sooner or later of biotechnological purposes.

The publication is a entire quantity describing Agrobacterium's biology, interactions with host species, and makes use of for genetic engineering.

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Agrobacterium: From Biology to Biotechnology by Tzvi Tzfira,Vitaly Citovsky

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