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By Egidio Del Fabbro, Akio Inui, Florian Strasser, David Blum, Hajime Suzuki

Cancer Cachexia is a concise, absolutely illustrated guide written with the purpose of accelerating information of melanoma cachexia and highlighting most sensible perform analysis, remedy, and administration strategies for this devastating illness. this can be one other identify within the ongoing Springer Healthcare melanoma Supportive Care Series.

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Effect of sexual dimorphism on muscle strength in cachexia. J Cachexia Sarcopenia Muscle. 2012;3:111-116. 15 American Thoracic Society. ATS Statement: Guidelines for the six-minute walk text. Am J Respir Crit Care Med. 2002;166:111-117. 16 Kilgour RD, Vigano A, Trutschnigg B, et al. Cancer-related fatigue: the impact of skeletal mass and strength in patients with advanced cancer. J Cachexia Sarcopenia Muscle. 2010;1:177-185. 17 Maddocks M, Byrne A, Johnson CD, Wilson RH, Fearon KC, Wilcock A. Physical activity level as an outcome measure for use in cancer cachexia trials: a feasibility study.

In males, free testosterone should also be measured (preferably in the morning) [13]. 46 • C an c e r c ac h e x i a Performance In order to assess overall performance status, there should be an estimation of a patient’s muscle strength. In specialized assessments, a test of hand-grip strength should be given, which is repeated twice on the dominant arm or once on each arm [3,14]. To measure lower body strength, a sit-to-stand time, six-minute-walk time, and gait speed can be a reliable tests [15,16].

2010;5:e148-e152. 67 Tohgo A, Kumazawa E, Akahane K, Asakawa A, Inui A. Anticancer drugs that induce cancer-associated cachectic syndromes. Expert Rev Anticancer Ther. 2002;2:121-129. 68 Fearon K, Strasser F, Anker SD, et al. Definition and classification of cancer cachexia: an international consensus. Lancet Oncol. 2011;12:489-495. 69 Mahmoud FA, Rivera NI. The role of C-reactive protein as a prognostic indicator in advanced cancer. Curr Oncol Rep. 2002;4:250-255. 70 Deans CC, Wigmore SJS. Systemic inflammation, cachexia and prognosis in patients with cancer.

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