Design Principles for the Immune System and Other by Lee A. Segel, Irun R. Cohen PDF

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By Lee A. Segel, Irun R. Cohen

Layout rules for the Immune process and different dispensed self sustaining platforms is the 1st booklet to ascertain the interior workings of the sort of number of dispensed independent systems--from insect colonies to excessive point laptop courses to the immune process. It deals perception into the interesting international of those structures that emerge from the interactions of probably self sustaining elements and brings us up to date at the kingdom of study in those parts. utilizing the immune procedure and sure features of its features as a main version, this publication examines some of the finest and troubling questions posed by way of advanced platforms. How do structures decide on the precise set of brokers to accomplish acceptable activities with applicable intensities at acceptable instances? How within the immune approach, ant colonies and metabolic networks does the diffusion and binding of a big number of chemical substances to their receptors enable coordination of procedure motion? What merits force many of the structures to complexity, and via what mechanisms do the structures focus on the tendency towards unwieldiness and randomness of huge complicated platforms?

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Extra info for Design Principles for the Immune System and Other Distributed Autonomous Systems (Santa Fe Institute Studies in the Sciences of Complexity Proceedings)

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26An Interpretative Introduction to the Immune System REFERENCES [1] Gray, D. Sem. Immunol 4 (1992): 29-34. [2] Hamilton, W. , R. Axelrod, and R. Tanese. " Proc. Natl. Acad. Sci. USA 87 (1990): 3566-3573. [3] Inman, J. K. " Theor. Immunol. (1978). [4] Janeway, C. , and P. Travers. Immunobiology: The Immune System in Health and Disease, 3d ed. , 1996. [5] MacKay, C. R. " Adv. Immunol. 53 (1993): 217265. , and J. W. Kappler. " Sci. Am. 269(3) (1993): 48-54. [7] Matzinger, P. " Ann. Rev. Immunol. 12 (1994): 991-1045.

The process of inducing an immune response. a complex of processes initiated in response to injury and leading to healing. Among the characteristics of inflammation are an increase in local blood flow and in permeability between blood and tissues, resulting in the recruiting of large numbers of immune cells to the site of the response arid the secretion of cytokines. that part of the immune system that depends on germline encoded receptors: it does not change or adapt to specific pathogens. a molecule that can elicit an adaptive immune response.

14] Piel, J. " Special Issue. Sci. Am. 269(3) (1993): 20-102. [15] Potts, W. , C. J. Manning, and E. K. Wakeland. " Nature 352 (1991): 619-621. [16] Segel, L. A. " In Proc. IEEE Conf. , Man & Cyber. Orlando, FL: IEEE Computer Society Press, 1997. , S. Forrest, and A. S. Perelson. " In Workshop Notes, Workshop 4'- Immunity Based Systems, Intnl. Conf. on Multiagent Systems, 62-70. Menlo Park, CA: AAAI Press, 1996. [18] Steinman, L. " Sci. Am. 269(3) (1993): 75-83. [19] Tonegawa, S. " Nature 302 (1983): 575-581.

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