Download e-book for iPad: Desk Encyclopedia of General Virology by Marc H.V. van Regenmortel, Brian W.J. Mahy
By Marc H.V. van Regenmortel, Brian W.J. Mahy
This quantity, derived from Encyclopedia of Virology, presents an summary of the improvement of virology over the last ten years. Entries element the character, beginning, phylogeny and evolution of viruses. It then strikes right into a precis of our understanding of the constitution and meeting of virus debris and describes how this knowledge was got. Genetic fabric of viruses and the several mechanisms utilized by viruses to contaminate and mirror of their host cells are highlighted. the quantity is rounded out with an outline of a few significant teams of viruses with specific recognition being given to our present wisdom in their molecular biology.
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Additional resources for Desk Encyclopedia of General Virology
Our understanding of the genome organization and functioning of viruses has come from the development of procedures whereby the complete nucleotide sequence of viruses with RNA genomes can be determined. In 1982 the genomes of both the first plant RNA virus (TMV) and DNA virus cauliflower mosaic virus (CaMV) were sequenced. Since then, the genomes of representatives of all the plant virus genera have been sequenced and there are many sequences of virus species. The late 1980s and 1990s was a period when molecular biological techniques were applied to a wide range of aspects of plant virology.
X-ray crystallography of crystals of purified isometric viruses has revealed the molecular structure of their icosahedra; similar revealing detail has been obtained for the neuraminidase and hemagglutinin spikes of influenza virus. Tumor Virology After the discovery of Rous sarcoma virus in 1911, there was a long interval before the second virus to cause tumors, rabbit papilloma virus, was discovered by R. E. Shope in 1933. However, after that viruses were found to cause various neoplasms in mice, and in 1962 J.
Holmes. This stimulated others, in particular C. H. Andrewes of London and A. Lwoff of Paris, to actions which resulted in the setting up of an International Committee on Nomenclature (later Taxonomy) of Viruses in 1966. Adopting the kind of viral nucleic acid, the strategy of replication, and the morphology of the virion as its primary criteria, this committee has now achieved acceptance of its decisions by the great majority of virologists. One interesting feature of its activities is that its rules avoid the controversies about priorities that plague taxonomists working with fungi, plants, and animals.