Download PDF by Alexander L. Greene: Encyclopedia of Stem Cell Research

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By Alexander L. Greene

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Title: Encyclopedia of Stem mobilephone Research
Author: Greene, Alexander L. (EDT)
Publisher: Nova technological know-how Pub Inc
Publication Date: 2012/06/23
Number of Pages: 1530
Binding kind: HARDCOVER
Library of Congress: 2010034298

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Chapter LII - The derivation of human embryonic stem cell lines from blastocyst stage embryos, first achieved almost a decade ago, demonstrated the potential to prepare virtually unlimited numbers of therapeutically beneficial cells in vitro. Assuming that large-scale production of differentiated cells is attainable, it is imperative to develop strategies to prevent immune responses towards the grafted cells following transplantation. This paper presents recent advances in the production of pluripotent cell lines using three emerging techniques: somatic cell nuclear transfer into enucleated oocytes and zygotes, parthenogenetic activation of unfertilized oocytes and induction of pluripotency in somatic cells.

The xl Alexander L. Greene Dickey amendment prohibits the use of Department of Health Human Services (HHS) funds for the creation of human embryos for research purposes or research in which a human embryo or embryos are destroyed, discarded, or knowingly subjected to certain risks of injury or death. The Dickey amendment thus prohibits the use of HHS funds to establish ES lines (line establishment involves embryo destruction), but not to conduct research using established lines. President Obama established current federal ESR policy with a March 9, 2009, executive order: Removing Barriers to Responsible Scientific Research Involving Human Stem Cells (Obama policy).

R. 877. Supporters assert that this facilitates research without ethical dilemmas. Critics characterize it as unnecessary, costly, and a diversion from developing treatments. Congress‘s third set of options involves discouraging ESR via tax measures, or limiting or eliminating it by restricting research funding, banning certain cloning techniques, or giving embryos the Constitutional right to life. R. R. R. R. R. 1654, S. 99, and S. 346. Supporters claim their approaches respect human dignity; critics claim they harm people already living.

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