Micro- and nanoelectromechanical biosensors by Leichlé, Thierry; Nicu, Liviu PDF
By Leichlé, Thierry; Nicu, Liviu
Most books devoted to the problems of bio-sensing are prepared via the well known scheme of a biosensor. during this e-book, the authors have intentionally determined to damage clear of the normal method of treating biosensing study through uniquely addressing biomolecule immobilization tools on a superior floor, fluidics matters and biosensing-related transduction concepts, instead of focusing easily at the biosensor. the purpose is to supply a modern photograph of the biosensing panorama with no neglecting the seminal references or items the place wanted, following the downscaling (from the micro- to the nanoscale) of biosensors and their respective top identified purposes. To finish, a short evaluate of the main popularized nanodevices utilized to biology is given, prior to evaluating biosensor standards when it comes to unique applications.
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Extra info for Micro- and nanoelectromechanical biosensors
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A qualitative interpretation of why the Sauerbrey relation loses applicability when the applied films are soft can be seen as follows [GIZ 02]: under such circumstances, the film does not follow the sensor’s mechanical oscillation as a “dead mass”, but is deformed in the shear direction, such as “a jelly lying on a plate”. The frequency shift caused by the jelly-like soft film does not correspond to its static mass but to a dynamic value that depends in a complex manner on its viscous and elastic components.
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