Download e-book for iPad: Microscopic Imaging Through Turbid Media: Monte Carlo by Min Gu, Xiaosong Gan, Xiaoyuan Deng


By Min Gu, Xiaosong Gan, Xiaoyuan Deng

This ebook presents a scientific advent to the foundations of microscopic imaging via tissue-like turbid media when it comes to Monte-Carlo simulation. It describes a number of gating mechanisms according to the actual variations among the un scattered and scattered photons and procedure for microscopic snapshot reconstruction, utilizing the concept that of the potent element unfold functionality. Imaging an item embedded in a turbid medium is a not easy challenge in physics in addition to in bio photonics. A turbid medium surrounding an item less than inspection motives a number of scattering, which degrades the distinction, answer and signal-to-noise ratio. organic tissues are usually turbid media. Microscopic imaging via a tissue-like turbid medium gives you better answer than transillumination imaging during which no target is used. This e-book serves as a priceless reference for engineers and scientists engaged on microscopy of tissue turbid media.

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Additional resources for Microscopic Imaging Through Turbid Media: Monte Carlo Modeling and Applications

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Here m denotes the degree of aggregation and m = 3 represents a homogeneously random medium. 2 < m < 3 gives the fractal degree description of a fractal aggregate in three-dimensional space that is represented by a spherical coordinate system shown in Fig. 7. Due to the structural feature of a fractal medium, the effective mean free path length (lm) for an aggregate is not simply related to the scattering cross section and the concentration of scattering particles in a homogeneously random medium (m = 3) rather than the following expression [23]: lm ¼ a½4ðm À 2Þ=KmQp Š1=ðmÀ2Þ ð3:35Þ where K and Qp are, respectively, the volume fraction of the fractal medium and the scattering efficiency of a scattering particle determined by the Mie scattering theory [14].

The scattering mean free path length, ls, is determined via ls ¼ 1 ; rs q ð2:11Þ where ρ is the concentration of particles per cubic micrometer and is given by q¼ 6W : ppd 3 ð2:12Þ Here p is the density of the scattering particles, W is the weight percentage of scatterers in a bulk solution and d is the diameter of scatterers. 8 nm Sphere diameter, κ (μm) Geometric cross-section, σg (μm2) Concent. 5 %. 1 shows the parameters for the four types of polystyrene microspheres used in Chaps. 8 nm. 1 it is seen that larger polystyrene microspheres have shorter scattering-mean free path lengths and higher anisotropy values.

2) only represents the imaginary depth, d′, into the turbid medium. This means that the true focal plane, d, defined by point E, into the turbid sample must be determined with the aid of Snell’s law [4]: n1 sin hi ¼ n2 sin h; ð3:5Þ where n1 and n2 are the refractive indices of the surrounding and turbid media, respectively. θi is the incident angle at which the ray of a projected photon, defined by points A and B, intersects with the turbid medium boundary at position C (see Fig. 2). It should be noted that in the Monte Carlo model spherical aberration is ignored.

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